Answer Posted / venkat.1830@gmail.com
acidic compounds are more retained at low ph ,basic
compounds are more retained at higher ph while neutral
compounds are uneffected. PH can be used as a powerful
selectivity tool for the separation of ionizable
compounds.At PH values used traditionally (PH 4-8 or
depending upon column specifications ),a change in PH can
result in a dramatic shift in retention
| Is This Answer Correct ? | 50 Yes | 2 No |
Post New Answer View All Answers
before starting analytical method valodation what you checking? and how giving preference to start validation?
if you given one product then which tests you will perform?
How doing qbd practically?
Which parameter require to do for analytical method equivalency?
how you determine moist.of NaOH sol or NaOH flacks
4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations
function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?
Hi sir if any product monograph not given known impurities (may be 5 impurities) specifications then how we require to proceed for inhouse formulation?
if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?
we can use expired sample for validation and analyst qualification?
mahagenco syllabus for the post of chemist
which are the sizes of capsules?
when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.
how you start RS method development when for new product?
what is the extinction coefficient for Indomethacin or at 319nm wave length.
