Answers were Sorted based on User's Feedback
Answer / lava khandelwal
MACO = Maximum Allowable Carryover (MACO), its limit could
be establish as below:
TDDprevious x MBS
MACO = ------------------------------
SF x TDDnext
MACO Maximum Allowable Carryover: acceptable transferred
the investigated product ("previous")
|Is This Answer Correct ?||7 Yes||0 No|
Maximum Allowable Carryover (MACO)is the limit of previous product in next product during cleaning validation.
can be calculated by the formula-
TD x BS xSF
MACO = ----------------
TD: single therapeutic dose of product A
BS : bach size of product B(minimum batch size)
SF: safety factor(1/1000) or 0.001
LDD : largest daily dose of product B
|Is This Answer Correct ?||3 Yes||0 No|
Why Naphalene only used in calibration of HPLC
How impurity is analyzed in any tablet?
What do you mean by Bracketing and Matrixing in stability?
why we use disodium tartarte for determination of factor in KF titration
What should be the LOD of dry syrup?
what do you mean by MACO
What is mean by partical size distribution.
What is limit of uniformity of content as per USP?
how you can fix the known and unknown impurity limit for any drug substance
What is medical representative role ?
Why Assay and CU test performed differently?
In Stability testing if significant change occur then what is the action plan?