amit chauhan


{ City } chandigarh
< Country > india
* Profession * executive qc
User No # 97247
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Question { 17471 }

what do you mean by MACO


Answer

Maximum Allowable Carryover (MACO)is the limit of previous product in next product during cleaning validation.
can be calculated by the formula-

TD x BS xSF
MACO = ----------------
LDD

where,
TD: single therapeutic dose of product A
BS : bach size of product B(minimum batch size)
SF: safety factor(1/1000) or 0.001
LDD : largest daily dose of product B

Is This Answer Correct ?    4 Yes 0 No

Question { Cipla, 25155 }

what is the composition of C18 column


Answer

octadecyl carbon chain bonded silica

Is This Answer Correct ?    50 Yes 1 No