When you get Moisture content by KF higher than by LOD,
what does this indicate?

Answer Posted / sandra nagarjuna

Case 1:KF will be more when samples contain lumps or big crystals
Case 2: If u r sample contain acetone or ketones ,in Kf method these two reacts with kf reagent and forms further water, so it will be more when compared to LOD

Is This Answer Correct ?    0 Yes 2 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

How doing qbd practically?

428


How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium

1983


What is column in chromatography?

1759


how you fix the limits of impurities?

381


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1793






What is delay volume?

847


If vendor having more imp than monograph then how to proceed? and how to set spec?

334


For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1247


how to calculate elemental impurities?

544


What is the use of tlc and hplc? And when and where use?

661


what is the disso medium for tropsiun chloride

1797


what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

338


What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

2116


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

1547


why digestion require in icpms?

305