why do u get different drug release while doing calibration
of dissolution test appratus 1& 2(paddle & basket)?
- 1 Answers
- 6432 Views
- HDFC, Medrich, Twilight Litaka Pharma, I also Faced
- E-Mail Answers
Answer Posted / sachin
When we calibrate with paddle at prescribed time it gives less release compare to basket release due to surface attachement of tablet or contact area of tablet.
| Is This Answer Correct ? | 7 Yes | 0 No |
Post New Answer View All Answers
what is partion and column chromatography
In rs method development when we are going area normalization method to dilute standard method?
what is biorelivent dissolution media?
EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE
how much mass should be there in volumetric flask while in preparation of sample for assay?
How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?
Which parameters require to do in tech transfer?
Which parameter require to do for analytical method equivalency?
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio
acceptance criteria for lod & loq by standard deviation of response and slope??
How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain
If vendor having more imp than monograph then how to proceed? and how to set spec?
How to set analytical specification for combination products?
Is it nessesary all multimedia dissolution require descriminatory?
