what is karl fischer principle and reaction ,describe it

Answer Posted / deepika hemant bankhede

A Quantitative chemical reaction between water and
Anhydrous SO2 and Iodine in the presence of Base(buffer)
that reacts H+.And the amount of water present in the sample is calculated
based on the concentration of iodine in the Karl Fisher
titrating reagent (i.e., titer) and the amount of Karl
Fisher reagent consumed in the titration. and the amount of Karl
Fisher reagent consumed in the titration. Macanism of action- H2O+I2+SO2+CH3OH+3RN=[RNH]SO4CH3+2[RNH]I

Is This Answer Correct ?    2 Yes 1 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

How doing qbd practically?

432


Related substance method equivalency on control sample or spiked sample?

304


Why Ethanol is Used for Standardization of GC Head space?

3722


if rsd failed then what require to do?

326


Why dissolution test is not performed in all of the products

2038






My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards

1113


UV and PDA detector, which have less signal to noise ratio?

648


Why six unit used for precision?

803


what is mean by dissolution biowaiver study?

328


mode of absorption in alimentary canal?

1921


cefoperozone and sulbactam inj. hplc test method

2132


how many types of balance calibration test?

1731


which batch require to use for analytical method validation?

335


acceptance criteria for lod & loq by standard deviation of response and slope??

2095


How to determine water content of bis tetrazole amine mono ammonium salt

2967