What is the difference between uplc and hplc
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Answer Posted / k.lavanya
HPLC is high performance liquid chromatography, whereas UPLC is ultra high performance liquid chromatography
In essence, UPLC is just a special variant of HPLC
The pump pressure, which is 40Mpa (400 atmospheres) in HPLC, can go up to 100MPa in UPLC. UPLC also allows for much smaller particle size, normally less than 2um whereas it is normally 5um in HPLC.
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