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Answer Posted / dharani kumarraju
Adsorption
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in api coa contains only process impurities and in product coa contains degradation impurities?
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?
How doing qbd practically?
how can give the expiry period and restadardisation of volumetric solution
EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE
what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means
how you fix the limits of impurities?
why we are using benzene, anyline in acetic anhdride assay titration method?
Difference between hlaf and rlaf
In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )
how we can identify the impurity is coming below loq at transfering site?
in which situation require to change rs specification?
What is viod volume and peak purity in HPLC?
why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?
