how do you perform reverse enginearing study for drug
containing sodium chloride sodium citrate sodium bicarbonate

Answer Posted / rahull

Determination of sodium chloride can be done potentiometricaly by using a silver electrode, sodium citrate can be determined by using a polar embedded column on a HPLC, sodium bicarbonate can be estimated by titration, alternatively it can be done by using ion chromatography which will estimate all three component ions.

Is This Answer Correct ?    0 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?

2275


How do we fix the sample concentaryion in hplc method development?

665


Difference between the quantitative analysis and qualitative analysis?

625


What is the Formula for coreletion coefficient in plhplc calibration

1240


in which situation ion pair require to use?

279






Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

1165


Why only 1.2 million lux hours require in photostability study?

460


Why irmoisture balance is used for corrugated box moisture testing

1927


what is mean by nitrosamine impurities?

538


give clarity of linearity and range in method validation

1862


which are the sizes of capsules?

404


WHY pKa value is more important than pH value of the mobile phase in HPLC?

1255


In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

2709


In which situation we require to prepare the standard solution from sample in Related substance method?

287


How would you decide dissolution medium for NCE compound of class I drug

1704