What is the reason for using the 900ml of dissolution medium

Answer Posted / kiranmadineni

the media volume shold be more than 3 times of the drug
dosage saturation amount. that maybe 500ml,900ml,1000ml.

Is This Answer Correct ?    17 Yes 1 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Why potassium dichromate is used in calibration of uv?

1397


Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?

2327


how to get accurate result for Residue on evaporation in purified water

1124


why we use glass fiber filters use in some situation?

326


While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2353






what is classification of elemental impurities? what is risk assement in elemental impurities?

344


why cone formation during dissolution?

325


we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1360


how much mass should be there in volumetric flask while in preparation of sample for assay? 

2059


in each media we require to use SLS? how to proceed?

301


WHAT IS THE PURPOSE WE USE HCL, CHOPPER, BURNER, MONOCHROMATOR in AAS? PLEASE EXPLAIN BRIEFLY

2106


how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1837


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1797


in api coa contains only process impurities and in product coa contains degradation impurities?

324


about method developement in hplc

1220