In lcms analysis some times we get sodium and potassium
adducts. if the compound is havine sodium ions how can we
confirm wether sodium is from sample or it is a adduct?

Answer Posted / spgoswami

If the precursor is sodium ion then intense peak will be of
sodium only rather than the same adduct so we can conclude
by observing lc-ms /TIC chromtgram
Regards

Is This Answer Correct ?    0 Yes 1 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

why glutent are detected in the rice cereal baby food product even manufacturer claimed that they are using rice and milk only?we have using ELISA to do the test,and rice supposed not containing any glutent,rite?We already repeat the test so many times and it still detected.just wondering where the glutent came from?

2348


WHAT IS THE PARAMETER FOR THE SELECTION OF MOBILE PHASE IN HPLC?

650


on saturation solubility study data how we can find out the bcs class of drug?

365


If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

361


mahagenco syllabus for the post of chemist

5744






What is rs test why we are performing rs test?

1308


how we can identify the impurity is coming below loq at transfering site?

387


How much is the standard area for glc analysis

1753


USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

1560


how to calibrate hplc & gc

4035


what is definition of validation? which components are followed give detail?

1831


what is classification of elemental impurities? what is risk assement in elemental impurities?

344


using gradient pressure in gas chromatography are not ?using gradient pressure why

2942


Which is the highly polar and highly non polar column in HPLC?

1787


How would you decide dissolution medium for NCE compound of class I drug

1710