From where 16 or 5.545 is derived in theoretical plates
calculation formula by USP or JP/BP/DAB and what is meaning
of this coefficient and impact in calculation ?

Answer Posted / dr. sp goswami

it comes auto width algorithm, also by calc of plate
thickness and how many plates can be in imaginery plates
when width is measured at 13.4% of the height(USP),50%(JP)%
By tangent to the baseline so every time due difference in
percent height calc in USP,JP, BP,DAB,EMG and 5sigma,4
sigma ,3 sigma there will be different values for this
coefficient like 16(USP),5.545(jp) etc
regards

Is This Answer Correct ?    6 Yes 3 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

What is delay volume?

857


Related substance method equivalency on control sample or spiked sample?

306


what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

2231


what is mean by nitrosamine impurities?

546


What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8317






what is mean by 40 in the dissolution basket mesh size?

298


Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6

2113


how can I make the copper get white bye any salt or acit?

1667


how to select short coloum and long coloumn for new molecule

1822


in which situation require to use paddle and basket?

293


what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

349


What is intact assay method development.....?

2008


in dissolution why pool sample needed? in which type of drug pool sample need?

2596


How to establish relative response factor for hplc. Why it is required?

709


how you start the solubility study?

346