Answer Posted / amit

Selection of disoslution media depends on the sink
condition which means, three time the highest dose of drug
dissolving in 250 ml of media. So, if your drug diosslves
in 250ml you can select 250ml as mediavolume or depending
on the solubiliy you can go upto 2 lts with proper
justification.
Remember the selection of dissolution media volume is only
to get whole amount of drug dissolved and sholud be able to
quantifiy it.

What is the use of tlc and hplc? And when and where use?

663

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What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

1551

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in which situation require to use paddle and basket?

293

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how many types of balance calibration test?

1733

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what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?

1521

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what is the procedure for cleaning of lenses of hatr accesory of ftir instrument?

1805

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what is third integration

1499

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if you have given one product then how you determine the impurity in that?

294

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We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

1322

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inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

293

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In rs method development when we are going area normalization method to dilute standard method?

946

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in each media we require to use SLS? how to proceed?

301

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In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )

2959

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how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1837

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please explain about aluminium hydroxide assay

709

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