why using buffers in hplc inteed of water

Answer Posted / m.balram naidu

BUFFERS IS USED TO DEPAND UP ON THE DRUG PKa VALUES
BUFFERS PH IS ALLWAYS (+) OR (-)1
BECAUSE IS USED PHASPATE OR ACETATE BUFFERS IS USED

Is This Answer Correct ?    1 Yes 2 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?

334


Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

307


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1183


in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?

340


if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

280






what is mean by extactable and leachable study?

574


CAN WE DETERMINE THE PEAK PURITY IN GAS CHROMATOGRAPHY ANALYSIS?

711


[3/28, 20:52] Manoj P Venkatpurwar: how many impurities require to inject in assay specificity that how we can find out? and in Rs also how?

355


In the isomers,enantiomers give the only physical properties present such that no chemical properties present.

1779


if you have given one product then how you determine the impurity in that?

294


if content uniformity passing but dissolution varrying then what is next step?

392


which batch require to use for analytical method validation?

339


If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

1757


how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1837


What is dose dumping? why require to do?

306