What is difference between Chromatographic purity and
Related substances analysis?
- 3 Answers
- 22112 Views
- I also Faced
- E-Mail Answers
Answer Posted / arumugam
chromatographic purity is %area normalization is nothing
but Impurity area/Major compound area, applicable for all
known and unknown impurities.
But Related substances is quantification of all impurities
nothing but the impurities are quantified by know
concentration of standard solution.
Impurity (%w/w)= Imp area* Std. Dilution*Potency of Std*RRF
------------------------
Std Area* sample Dilution
RRF= Relative Response factor
| Is This Answer Correct ? | 27 Yes | 1 No |
Post New Answer View All Answers
how we can identify the impurity is coming below loq at transfering site?
which are the sizes of capsules?
what is the principle of UV Vis spectroscopy, AAS, ICP OES,ICPAES, ICP-MS and FTIR
what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?
about method developement in hplc
Why irmoisture balance is used for corrugated box moisture testing
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
What is the difference between spectro meter and spectro photo meter?
in which situation require to take incident in validation?
all types of questions asked at the cipla interview
what is diffrence between specificity and selecivity?
which batch require to use for analytical method validation?
In which situation we require to prepare the standard solution from sample in Related substance method?
what is classification of elemental impurities? what is risk assement in elemental impurities?
How we choose the mobile phase for method development.?
