what is the need of calulation of RRF of impurity in HPLC
analysis?

Answer Posted / ramesh babu

Generally RRF will calculate in impurity analysis. The
impurity standards are very cost effectives and some times
not avalible. It is not possible to use the impurity
standard at each time of the impurity analysis.During the
method development time we need to calculate RRF against
with standard.

Is This Answer Correct ?    44 Yes 9 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

why cone formation during dissolution?

325


Basic principle of ESI?

1646


What is stray light in uv what are units for stray light

1026


which are the diffrent batches in the pharmaceuticals?

347


why require to do water content for drug product?

319






Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

306


Why we select scan range from higer wavelength to lower wavelength in uv visible spectroscopy and ftir spectroscopy ? .

462


process of Diclofenac sodium,IP.

1677


Which are the diffrent grades of api in pharma?

317


How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

3599


Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?

2327


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1183


what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?

9439


What is Band broading effect explain

1400


which are the sizes of capsules?

409