Why we use caffeine for HPLC calibration in Detector wave
ength accuracy test
Answer Posted / atul ingle
Why we use it, Because of
# It gives a multiwavelength response like 205,245,273 nm
# It is easily available in market
# It is very stable, we can use a long time foranalysis
i.e. it is not degradable
# It is chip
Is This Answer Correct ? | 173 Yes | 13 No |
Post New Answer View All Answers
why require to do water content for drug product?
how to get accurate result for Residue on evaporation in purified water
how to calculate elemental impurities?
How can I develope method of dissolution by HPLC OR UV
How can we confirm the HPLC column is end-capped or not? Is it possible to identify by physical appearance?
Why irmoisture balance is used for corrugated box moisture testing
Which is the highly polar and highly non polar column in HPLC?
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
why require the ph, buffer during hplc mobile phase?
Please give idea about method development for cleaning method and how maco level establish
In which situation we require to analytical method validation of excipient?
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?
If vendor having more imp than monograph then how to proceed? and how to set spec?