Did HIV 1 & 2 speard through meanstural cycle?
Answer Posted / nithya.ng
The human immunodeficiency virus type 1 (HIV-1) infects
cells within mucosal tissues, including those of the female
reproductive tract (FRT). The mechanism of viral
transmission within the FRT and the mode of viral spread to
the periphery are not completely understood. We performed
phenotypical analyses and infectivity studies of primary
FRT cells to identify potential targets of infection within
the FRT. Our findings indicate that expression of HIV-1
receptors and coreceptors in the FRT varies as a function
of menstrual-cycle stage, suggesting that sex hormone
levels may influence a woman’s susceptibility to infection
by HIV-1. Moreover, HIV-1 strains that utilize the CXCR4
chemokine receptor for infectivity are able to undergo
reverse transcription, integration, viral DNA
transcription, and viral release, whereas viral strains
that utilize CCR5 do not undergo these early replicative
events, and are only released unmodified from these cells.
This indicates that several mechanisms for viral infection
and transmission are present throughout the FRT.
Is This Answer Correct ? | 3 Yes | 1 No |
Post New Answer View All Answers
Explain the mechanism of antibacterial action?
How to improve co-transformation efficency?
Describe the process of Making high electrocompetent coli (DH5a or Top10) ?
Explain the meaning of bioremediation and describe four examples where microorganisms have been used or can be used in bioremediation?
Describe about the bacterial hydrogenase activity in hydrogen production ?
Explain about b-D-glucosidase?
How does ELISA work?
Which microbes are present in pharmaceuticals?
Is quaternary ammonium safe?
How is the smear graded?
Where to do genomic base composition analysis?
What are cold methods of acid fast staining?
Explain the Electrotransformation to lactobacillus delbrueckii ?
What is the procedure of anti-viral test ?
Name some disinfectants?