how do you established the RRF for unknown impurity
Answer Posted / babasaheb gilbile
RRF calculation required same cons for impurity and main compounds solution. with help of HPLC this solution measured area response for Impurity and Main peak.
Then calculated RRF= Area response of Impurity/ Area response of Main peak
| Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?
what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me
how we can identify the impurity is coming below loq at transfering site?
why are measure gas flow " ml " in Gas chromatography
In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )
how require to interprit the method precision data of hptlc?
What is the principle of Thermal conductivity detector and FID?
What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.
what is mean by ambient temperature?
How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?
why we use a particular hplc column for a particular compound give reasons?please
How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium
[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?
In rs method development when we are going area normalization method to dilute standard method?
EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE