Answer Posted / rishabh

First of all check your compound solubility in which solvents then after that based on solubility the Mphase selection becomes easy if compound is soluble in aqueous medium check the pH of that medium than after further procced if not then check the solubility in organic solvents on basis of solubility and pH of the Mobile phase. Both Mobile phase selection and stationary phase are selected.

What is aggregate and fragments in SEC?

2093

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What are modes of quantification in related substances

2149

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if you have given a blank water how you analyse by general analytical techniques?

2014

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USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

1996

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UV and PDA detector, which have less signal to noise ratio?

1118

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why we are using benzene, anyline in acetic anhdride assay titration method?

2096

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if tech transfer fails whay require to do?

822

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on the basis of bcs class how to proceed the solubility?

740

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What is third generation HPLC Columns?

1968

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How much is the standard area for glc analysis

2261

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if identification threshold crosses the limits then what next step?

844

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What is column in chromatography?

2214

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inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

697

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How we can identify process related and degradation impurity in single method with short period?

794

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if content uniformity passing but dissolution varrying then what is next step?

852

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