Why perform dissolution multimedia study in dissolution
Development

Answer Posted / manas

since body consist of different mediums,we perfom disso test in different media to make sure which media is suitable for a specific entity(drug) to give a maximum dissolution disso graph/value.
Taking into acccount of a new drug formulation when we are not sure about the media to perform disso or not specified in OGD,so multi-media disso is recommended to make sure of the disso media for a drug.

Is This Answer Correct ?    3 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6

2103


what is mean by peak intigrity?

335


why cone formation during dissolution?

314


how to decide for one product require water content or LOD?

323


What is shaking level in GC?

326






If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

1751


what is the extinction coefficient for Indomethacin or at 319nm wave length.

3513


What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1141


how to calibrate hplc & gc

4026


why require the ph, buffer during hplc mobile phase?

401


We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

1311


1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1300


What is column in chromatography?

1757


using gradient pressure in gas chromatography are not ?using gradient pressure why

2934


In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?

455