Why perform dissolution multimedia study in dissolution
Development
Answer Posted / manas
since body consist of different mediums,we perfom disso test in different media to make sure which media is suitable for a specific entity(drug) to give a maximum dissolution disso graph/value.
Taking into acccount of a new drug formulation when we are not sure about the media to perform disso or not specified in OGD,so multi-media disso is recommended to make sure of the disso media for a drug.
| Is This Answer Correct ? | 3 Yes | 0 No |
Post New Answer View All Answers
[3/28, 20:52] Manoj P Venkatpurwar: how many impurities require to inject in assay specificity that how we can find out? and in Rs also how?
if content uniformity passing but dissolution varrying then what is next step?
what is the disso medium for tropsiun chloride
how to develop the icp ms method? Application of icp ms?
If vendor having more imp than monograph then how to proceed? and how to set spec?
How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?
What is the requirement for brazil in the analytical method vslidation comparr to ich?
what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means
which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc
4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations
in stress study if your api not soluble in hcl naoh h2o2 then what require to do?
why octanol used to determine the partition coefficient ?
How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample
we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
Principle of single pan analytical balance