Interested to Buy Any Domain ? << Click Here >> for more details...
How to calculate LOD & LOQ in HPLC Validation Method
- 14 Answers
- 116129 Views
- Dr Reddys, GSK GlaxoSmithKline, Reddy Labs, Reliance, UIS, I also Faced
- E-Mail Answers
Answer Posted / nunu
"ashutosh kumar srivastava
Signal of noise ratio X 3 = LOD
LOD X 3.33 =LOQ"
Hi, could you pls explain the meaning of the coefficient 3.33 in LOD X 3.33 =LOQ. Thanks!
| Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
in stress study if your api not soluble in hcl naoh h2o2 then what require to do?
is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth
If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?
Many times I don't got a caffeine peak in calibration of hplc using guard column ❓
effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?
what is biorelivent dissolution media?
How to know the estimated LOQ concentration in ppm
What is dose dumping? why require to do?
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
Basic principle of ESI?
please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development
Why only hydroxy naphthol blue indicator is used for standardisation of 0.05M EDTA solution instead of solochrome Black T or Euriochrome Black T indicator which is used for all sample analysis with 0.05M EDTA solution?
we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
in hplc chromatogram started from left to right and in uv spectrum started from left to right
how you establish the LOQ?
