Answer Posted / ichinnakamisetti

The USP clearly states for dissolution sampling, the sample should be withdrawn from a zone midway between the surface of the dissolution medium and the top of the rotating paddle or basket and not less than 1cm from the wall.

How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?

735

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What is viod volume and peak purity in HPLC?

2884

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WHY pKa value is more important than pH value of the mobile phase in HPLC?

1772

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why holium oxide prepared in 10% HCLO4 SOLUTION

1462

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give clarity of linearity and range in method validation

2420

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in which situation ion pair agent require to use?

740

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What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8865

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What is rs test why we are performing rs test?

1865

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what are the guidelines for analytical method validations?

1106

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Please give idea about method development for cleaning method and how maco level establish

753

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how to develop the icp ms method? Application of icp ms?

812

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we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1872

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which situation gc hs and gc als require to use?

793

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In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3130

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Why sodium hydroxide used for maintain pH of phosphate buffer

2415

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