Answer Posted / ram krishna

Normal phase _Column is polar and more is non polar sudh as IPA hexane
Reversed phase_Column is non polar and more is polar such as water and acetonitrile mp

How to set analyticl specification for combination products?

756

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how you establish the LOQ?

801

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How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

3367

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[3/28, 20:52] Manoj P Venkatpurwar: how many impurities require to inject in assay specificity that how we can find out? and in Rs also how?

798

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if you get peak in blank then what require to do?

981

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In IR spectra, generally a molecule vibrates without apply emr or ir light?

1986

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process of Diclofenac sodium,IP.

2222

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what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

2632

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if identification threshold crosses the limits then what next step?

877

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Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?

2837

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which are the diffrent batches in the pharmaceuticals?

826

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I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

3546

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some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2659

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what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

901

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in which situation require to take incident in validation?

1738

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