what split ratio in gas chromatography.

Answer Posted / khaja mohinuddin

Capillary columns are easily overloaded by injecting High Amount of Sample Concentration.
To Reduce or overcome this problem Split Ratio is Incorporated The Main use of this Split Ratio is Inject Less amount of Sample of interest into column or passes through it.
The Q? comes in a mind How it could be Done
Split vent is option Provide by Every manufacture like Agilent and shimadzu how it works i will expalin
Example :- ur method shows a split ratio of
1:30 Metan that 150ml/min of Split vent flow and Colum flow 5ml/min If u have Installed 0.53mm id Colum of any pahse.
Similarlly 1:50 mean 250ml/min of split ventflow and 5ml/min of column flow

formula split ratio = split vent flow / column flow
if know any of the parameter u can calculate by substituting in the above formula ...


thanks

Is This Answer Correct ?    7 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

2592


In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

2697


in which situation require to change rs specification?

260


in which situation require to use paddle and basket?

277


Which parameter require to do for analytical method equivalency?

307






Difference between hlaf and rlaf

1637


all types of questions asked at the cipla interview

4131


Qc interview questions

1242


what are the guidelines for analytical method validations?

582


some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2090


which situation gc hs and gc als require to use?

288


for which product require to do content uniformity? what is limit of cu?

300


if you given one product then which tests you will perform?

309


How we can identify process related and degradation impurity in single method with short period?

315


what is classification of elemental impurities? what is risk assement in elemental impurities?

328