What is the reason of RT change in new column v/s old column in HPLC

Answer Posted / arul

old coloumn inside some particles may be formed, new coloumn no particles that is reason

Is This Answer Correct ?    2 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

what is the purge flow & how to calculate

1968


how we can identify the impurity is coming below loq at transfering site?

376


In rs method development when we are going area normalization method to dilute standard method?

933


Related substance method equivalency on control sample or spiked sample?

297


What is split ratio in Gc? Splitless? how requirr to select?

316






What is related substance by HPLC impurity limits as per USP?

545


what is third integration

1484


What is column in chromatography?

1755


How to set analytical specification for combination products?

314


WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

2132


how decide the clining method and cleaning method validation require for this perticular products?

295


For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1234


How can we calculate offset value pH measurment

1062


Which parameter require to do for analytical method equivalency?

311


if content uniformity passing but dissolution varrying then what is next step?

375