why we are using sodium,potassium phosphates for mobile phase
preparation?
Answer Posted / kiran ambekar
Generally phosphate buffer is used fro preparation of buffer
in reversed phase bcas phosphate buffer has 3 Pka ie. 2.1,
7.2, 12.3.
Generally potassium salt is used because potassium salt has
more counter ion capability than sodium and ammonium. Also
potassium salt has more solubility in buffer than other salt
| Is This Answer Correct ? | 5 Yes | 0 No |
Post New Answer View All Answers
in which situation require to use paddle and basket?
What is aggregate and fragments in SEC?
How can we confirm the HPLC column is end-capped or not? Is it possible to identify by physical appearance?
why salisylic acid not using now days for disdolution calibration?
please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development
How much is the standard area for glc analysis
USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...
in gas chromatography what is the difference between gas flow rate and average linear velocity ?
why cone formation during dissolution?
In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?
inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?
EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE
why we are using benzene, anyline in acetic anhdride assay titration method?
Tell me about analytical method validation in QC
If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?