Answer Posted / venkata padmanabheswara rao

Primary Standard:
A substance that is widely acknowledged to have the
appropriate characteristics within a specified context and
whose value is accepted without requiring comparison to
another substance, this substance should be obtained from
official recognized sources.

Secondary
A substance of established quality and purity as shown by
comparison to a Primary standard used as a Secondary
standard for routine laboratory analysis. It serves as a
substitute for its corresponding Primary standard.

in api coa contains only process impurities and in product coa contains degradation impurities?

685

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how you confirm the assay method?

749

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in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

806

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if rsd failed then what require to do?

817

---

why multimedia dissolution require to do?

793

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How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?

3852

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which are the sizes of capsules?

943

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For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1895

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If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

2282

---

give clarity of linearity and range in method validation

2405

---

What is intact assay method development.....?

2628

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why lactose has less charges when packed in steel containers when compared with packing of lactose in polyamide material?

2286

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What is the use of tlc and hplc? And when and where use?

1135

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for inorganic molecules require to do RS, Assay and disso?

721

---

what is the disso medium for tropsiun chloride

2247

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