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How did you conclude that when stressing a compond, all
degradation products have eluted in chromatogram?
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Answer Posted / m.sivalingeswararao
By calculating mass balance.It should be equal to or nearer to 100%.%Decrease in mass balance indicates the % of Impurities not detected or not eluted. In some cases Degraded Impurities may not be eluted with in specified run time,in such cases they may elute in the next run ,hence it should be advisable to increase the run time.
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