How to select buffer for HPLC mobile phase

Answer Posted / kaushlendra singh

pH of buffer should be + or minus 1 away from pK of
compound and near to the pK value of buffer or salt use in
mobile phase preparation.

Is This Answer Correct ?    7 Yes 2 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

3585


What are modes of quantification in related substances

1713


what is mean by nitrosamine impurities?

533


1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1300


What is control room temperature and which guide line says?

1150






what is biorelivent dissolution media?

298


why multimedia dissolution require to do?

303


what is mean by 40 in the dissolution basket mesh size?

285


Why we check moisture,ash & AIA in product

1395


Why perchloric acid used for potentiometric titration

2152


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

1542


i want model written test paper for the post of analyst in IOCL(indian oil corporation ltd) any one pls help me

2181


What is mean by PDR?

322


what is mean by dissolution hydrodynamics?

341


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1177