Answer Posted / suresh palacharla

Depending upon maximum Daily Dose and thresholds. please refer ICH-Q3

What is the requirement for brazil in the analytical method vslidation comparr to ich?

270

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please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

1098

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WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE

1615

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Which is the highly polar and highly non polar column in HPLC?

1779

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why octanol used to determine the partition coefficient ?

1916

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in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?

263

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I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

2973

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what is mean by dissolution biowaiver study?

323

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if content uniformity passing but dissolution varrying then what is next step?

383

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for which product require to do content uniformity? what is limit of cu?

305

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WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

2137

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AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?

1605

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what is the extinction coefficient for Indomethacin or at 319nm wave length.

3515

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How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

2013

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why are measure gas flow " ml " in Gas chromatography

1152

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