What is the reason for using the 900ml of dissolution medium
- 16 Answers
- 74033 Views
- Cipla, I also Faced
- E-Mail Answers
Answer Posted / amit
Selection of disoslution media depends on the sink
condition which means, three time the highest dose of drug
dissolving in 250 ml of media. So, if your drug diosslves
in 250ml you can select 250ml as mediavolume or depending
on the solubiliy you can go upto 2 lts with proper
justification.
Remember the selection of dissolution media volume is only
to get whole amount of drug dissolved and sholud be able to
quantifiy it.
| Is This Answer Correct ? | 33 Yes | 6 No |
Post New Answer View All Answers
WHY given much noise PDA dector then VWD Dector
iam usig ph buffers merk. manually how to prepare ?
What is control room temperature and which guide line says?
Why are use silicon oil mr?
how the compound separate in coulunm,explain
how to set sample and standard concentration in RS method?
How can I develope method of dissolution by HPLC OR UV
What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.
give clarity of linearity and range in method validation
What is the principle of Thermal conductivity detector and FID?
In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )
If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?
While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?
How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.
what is the principle of UV Vis spectroscopy, AAS, ICP OES,ICPAES, ICP-MS and FTIR
