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What is the reason for using the 900ml of dissolution medium
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Answer Posted / amit
Selection of disoslution media depends on the sink
condition which means, three time the highest dose of drug
dissolving in 250 ml of media. So, if your drug diosslves
in 250ml you can select 250ml as mediavolume or depending
on the solubiliy you can go upto 2 lts with proper
justification.
Remember the selection of dissolution media volume is only
to get whole amount of drug dissolved and sholud be able to
quantifiy it.
| Is This Answer Correct ? | 33 Yes | 6 No |
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