Answer Posted / godhani pragnesh

RRF= Relative response factor (Impurity response with
respact to main peak)
RF= Response factor (the response (e.g. peak area) of drug
substance or related substances per unit weight.

RF= peak area / concentration (mg/ml)

Relative response factor (RRF)calculation:

RRF=RF impurity / RF API

OR

RRF=slope impurity / slope API

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