only one end point is possible for citric acid and we get 2
end points for di acid why?
Answer Posted / balakrishnan
Actually Citric acid is having three COOH group, due to
this we should get three end point. This can be acheived by
using potentiometry titration(Measure the pH variation with
respect to Volume added). The pKa values are 3.15, 4.77 and
5.19. Each pKa contributes one end point.
Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
why are measure gas flow " ml " in Gas chromatography
In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
why we use a particular hplc column for a particular compound give reasons?please
WHAT IS THE PURPOSE WE USE HCL, CHOPPER, BURNER, MONOCHROMATOR in AAS? PLEASE EXPLAIN BRIEFLY
Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
what is mean by dissolution hydrodynamics?
IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?
USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.
how will you do the prep for unstable componds?
why we are using benzene, anyline in acetic anhdride assay titration method?
What is the Formula for coreletion coefficient in plhplc calibration
identification is for unknown? qualification for known? reporting for LOQ?