What is the difference between Paddle and Basket Why we are
using Basket or paddle in dissolution.

Answer Posted / dhiraj kumar

Generally we are using basket in those tablets in which HPMC is using as a binder because if HPME will come to contract with water then it will show sticky correcter and the tablet in which HPMC is used as a binder will get swell and stick with vessel and drug is not release because tablet will not move properly but in basket tablet is in the center of the vessel and so drug will release continue.

Is This Answer Correct ?    52 Yes 6 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

how to set sample and standard concentration in RS method?

354


in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

342


What is the diffrence in japan mkt requirement in analytical method validation over US?

286


what is the difference between potentiometric titration and karl fischer titration?

2414


What is the Formula for coreletion coefficient in plhplc calibration

1236






What is similarity factor and its use in api strength?

785


How to start the dissolution development for unknown tab?

1138


EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE

2126


identification is for unknown? qualification for known? reporting for LOQ?

272


which are the sizes of capsules?

398


If combination product how require to identify which imp is of which api?

315


what type of question will ask in the interview of lab chemist.

2882


1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1300


What is importance of pH in the Heavy metal test and How it effect on the test results?

1744


what is mean by 40 in the dissolution basket mesh size?

287