Answer Posted / rahul jain

The concept of Peak purity is generally used in HPLC using PDA detector. PDA detector scan a single peak at various points, if peak is pure than the uv spectrum of peak at different points will be same but if peak is not pure than uv spectrum of peak at different points will not be same.

In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3127

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in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?

750

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Why potassium dichromate is used in calibration of uv?

1983

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can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

2178

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why we use glass fiber filters use in some situation?

797

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when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

2040

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Why we use potassium dichromate in uv calibration Exact reason behind it??

1255

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what is mean by ambient temperature?

914

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how you start RS method development when for new product?

718

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Why six unit used for precision?

1344

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in each media we require to use SLS? how to proceed?

784

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how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

2286

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how require to interprit the method precision data of hptlc?

821

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in which situation ion pair require to use?

814

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UV and PDA detector, which have less signal to noise ratio?

1130

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