Answer Posted / vikky

In water by KF test we can determine water content only
whera as in LOD test we can determine % of volatile
Solvents and water in drug substance.

Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?

2709

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how much mass should be there in volumetric flask while in preparation of sample for assay? 

2553

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How do we fix the sample concentaryion in hplc method development?

1119

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Which parameters require to do in tech transfer?

734

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

834

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in stress study if your api not soluble in hcl naoh h2o2 then what require to do?

820

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we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1849

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What is the difference between purge septum flow and column flow in gas chromatography?

2548

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WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

2561

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What is similarity factor?

1175

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why does used dry caffien in HPLC calibration?

2015

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is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

2155

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4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations

2696

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UV and PDA detector, which have less signal to noise ratio?

1117

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How will u perform degradation study in detectors other thann PDA in HPLC Methodology

2518

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