Answer Posted / vishal shah

In TOC calibration 1,4 Benzoquinone used because 1,4
Benzoquinone is tufest to oxidized and sucrose is easly
oxidized so cover upper and lower range for calibration.

In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3101

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what is classification of elemental impurities? what is risk assement in elemental impurities?

743

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what is mean by extactable and leachable study?

1141

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what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1952

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what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

4465

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Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc

1448

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Why sodium hydroxide used for maintain pH of phosphate buffer

2381

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how to calibrate hplc & gc

4488

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How much is the standard area for glc analysis

2260

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WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE

2111

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How to determine water content of bis tetrazole amine mono ammonium salt

3461

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How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

2293

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if you get peak in blank then what require to do?

947

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What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1583

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In which situation we require to prepare the standard solution from sample in Related substance method?

755

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