Answer Posted / prasad

Because Only holmium can give sharp peaks in both UV and
Vis range, Sharp peak is very rare in UV/Vis spectroscopy.
It is very stable and doesn't absorb light at lower
wavelength.

If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?

733

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Which parameter require to do for analytical method equivalency?

729

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Hi sir if any product monograph not given known impurities (may be 5 impurities) specifications then how we require to proceed for inhouse formulation?

651

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how decide the clining method and cleaning method validation require for this perticular products?

705

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Why we check moisture,ash & AIA in product

1821

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please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

1575

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if tech transfer fails whay require to do?

771

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Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

1744

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before starting analytical method valodation what you checking? and how giving preference to start validation?

749

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what is third integration

1928

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How much is the standard area for glc analysis

2210

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in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?

665

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If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

2240

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

796

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please explain about aluminium hydroxide assay

1091

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