Did HIV 1 & 2 speard through meanstural cycle?
Answer Posted / nithya.ng
The human immunodeficiency virus type 1 (HIV-1) infects
cells within mucosal tissues, including those of the female
reproductive tract (FRT). The mechanism of viral
transmission within the FRT and the mode of viral spread to
the periphery are not completely understood. We performed
phenotypical analyses and infectivity studies of primary
FRT cells to identify potential targets of infection within
the FRT. Our findings indicate that expression of HIV-1
receptors and coreceptors in the FRT varies as a function
of menstrual-cycle stage, suggesting that sex hormone
levels may influence a woman’s susceptibility to infection
by HIV-1. Moreover, HIV-1 strains that utilize the CXCR4
chemokine receptor for infectivity are able to undergo
reverse transcription, integration, viral DNA
transcription, and viral release, whereas viral strains
that utilize CCR5 do not undergo these early replicative
events, and are only released unmodified from these cells.
This indicates that several mechanisms for viral infection
and transmission are present throughout the FRT.
| Is This Answer Correct ? | 3 Yes | 1 No |
Post New Answer View All Answers
Explain the meaning of bioremediation and describe four examples where microorganisms have been used or can be used in bioremediation?
Describe the Influenza inoculation of Hek293 cells ?
What do you know about our company?
How to contaminate bacterial culture ?
What is meant by fungal element?
which cultures or subcultures or standards are generally using as a positive control for total aerobic microbial count in API?
After primary herpetic gingivostomatitis,where will be the herpes virus may remain dormant ?
Define miasma notion of disease?
what are the microbes that grow if proper temperatures are not maintained during fermentation process?
What are the advantages of quaternary ammonium compounds?
How molecular taxonomy has affected bacterial classification?
How to Preserve bacteria in PBS for immunization ?
Give an account of Rota virus - Plaque assay ?
How is air sterilized?
what is the protocol for immunoprecipitation of bacterial proteins?