Interested to Buy Any Domain ? << Click Here >> for more details...
why
we
have
to
use
only
900
ml
buffer
in
dissolution
apparatus ?
what
are
the
conditions
that
favours
the
selection
of
volume
of
buffer?
- 1 Answers
- 7075 Views
- I also Faced
- E-Mail Answers
Answer / t reddy
selecting volume of buffer depends upon the sink condition of the drug...
example: if ur drug maximum doasge is 500mg means.. take 3times of these dosage that is 1500mg... dissolve it 500ml buffer, there should not be any formation of precipitation in buffer... if there is any prcptn means increase the buffer volume until the drug getting completely dissolved... that will be the final volume for ur dissolution studies.
there is also another way 1st know the maximum solubility of dosage
example:if 500mg(consider this as 100%) in 900ml of buffer is the maximum solubility of the drug... then your doasge should not be more than 350mg(70%) in 900ml of buffer. u can use any dosage form less than 350mg for 900ml of buffer
| Is This Answer Correct ? | 6 Yes | 0 No |
How do you feel about physical restraints?
while formulation of Gliclazide floating tablets why we are using direct cmpression technique why not wet granulation and what happend with that
are vaccines for long term or short term?
2 Answers GSK GlaxoSmithKline,
What are the regulatory commitments in markets like USA, Canada, Europe, Brazil, South Africa and Japan
how many clauses are there in iso? give me the clauses details?
please e-mail me the model of Tamil Nadu drug inspector question papers
what is immunity?
5 Answers GSK GlaxoSmithKline,
concomitant administration of 6-mercaptopurine and which product results in severe bonemarrow suppression?
You will be required to interact with patients. Tell us about your previous experience with patients and how did you deal with the experience.
What is difference between Analytical method validation and Analytical method transfer?
who is the father of pharmacy?
Why SLS used as dissolution medium
Pharmacy 
