Difference between Totipotent and pluripotent stem cells?
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Answer Posted / indraneel
pluripotent refer to a stem cell that has the potential to
differentiate into any of the three germ layers: endoderm
(interior stomach lining, gastrointestinal tract, the
lungs), mesoderm (muscle, bone, blood, urogenital), or
ectoderm (epidermal tissues and nervous system).
Pluripotent stem cells can give rise to any fetal or adult
cell type. However, alone they cannot develop into a fetal
or adult animal because they lack the potential to
contribute to extraembryonic tissue, such as the placenta.
In contrast, many progenitor cells are multipotent, i.e.
they are capable of differentiating into a limited number
of cell fates.
Totipotency is the ability of a single cell to divide and
produce all the differentiated cells in an organism,
including extraembryonic tissues
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