What is split ratio in Gc? Splitless? how requirr to select?
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Answer Posted / S K Nigam
The split ratio in Gas Chromatography (GC) refers to the proportion of the eluent that is directed into the detector versus the proportion that is vented to waste. A high split ratio reduces the amount of sample reaching the detector, which can reduce column overloading and improve peak shape, but it also results in lower sensitivity. Splitless mode allows all of the eluent to reach the detector, increasing sensitivity but potentially leading to greater column overloading. The selection of a split ratio or splitless mode depends on various factors such as sample concentration, detector type, and the desired level of sensitivity.
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