Cystic fibrosis (CF) occurs with a frequency of about
1/2500 Caucasian newborns and is inherited as an autosomal
recessive. A woman had an older sister die from
complications of this disease. CF is not present among
relatives of her husband. Both the woman and her husband
have normal phenotypes. What is the chance this couple will
have a CF child
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Answer Posted / Surjeet Kumar Jha
{"Chance of CF Child": "The chance of having a child with cystic fibrosis is 25%, as both parents are carriers (heterozygotes) for the recessive allele, and there is a 1 in 4 or 25% probability of their child inheriting two copies of the affected allele."}
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