Answer Posted / b.gangatharan

Small scale Trials are generally taken in pilot plants before going for large scale production .
Thanks,
B.Gangatharan,
Caplin point,
Puducherry.

Why to use propyl paraben in HPLC gradient calibration

7360

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In which situation we require to prepare the standard solution from sample in Related substance method?

730

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In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3086

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2278

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Related substance method equivalency on control sample or spiked sample?

730

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in which situation require to use paddle and basket?

690

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Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

2836

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We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

1850

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What is viod volume and peak purity in HPLC?

2831

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Tell me about analytical method validation in QC

6137

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Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?

2685

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Why potassium dichromate is used in calibration of uv?

1938

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what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?

3628

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What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

7487

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give clarity of linearity and range in method validation

2395

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