How to decide the standard concentration for related substances hplc method

Answer Posted / deepakshewle84

Std con is decided on the basis of identification threshold mentioned in ich. Eg. Your sample concentration is 250ppm & identification threshold limit is 1.2% ans is 3ppm.

Is This Answer Correct ?    2 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?

3389


WHY pKa value is more important than pH value of the mobile phase in HPLC?

1255


What should be the level/ Percentage of Arsenic in Arsenic free zinc.

1760


Tell me something about Vitamin A test method by HPLC

2205


what is diffrence between specificity and selecivity?

308






Did anybody have method for acetyl cysteine effervescnce tablet

1808


please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

1098


What is the difference between purge septum flow and column flow in gas chromatography?

1834


what is the difference between potentiometric titration and karl fischer titration?

2420


Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?

2136


What is viod volume and peak purity in HPLC?

2334


Basic principle of ESI?

1642


how we can identify the impurity is coming below loq at transfering site?

382


if rsd failed then what require to do?

320


what are the standard methods for HPLC?

2241