Answer Posted / ramalingeswararao

Based on environmental conditions Based on Material of Construction we will take lead as a standard

Tell me something about Vitamin A test method by HPLC

2683

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please explain about aluminium hydroxide assay

1135

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on the basis of bcs class how to proceed the solubility?

786

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why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1713

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How to do regeneration of Metacarb Pb plus column?

2580

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For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1910

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If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

996

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how you fix the limits of impurities?

837

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How would you decide dissolution medium for NCE compound of class I drug

2265

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How we can identify process related and degradation impurity in single method with short period?

825

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Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?

2188

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

864

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How require to perform linearity as per ANVISA? What are the acceptance criteria?

1344

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If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

2310

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what is procedure of actual procedure for registration of drug?

2012

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