what is the Bracketing & Matrixing.
- 8 Answers
- 42056 Views
- Dr Reddys, Ranbaxy, I also Faced
- E-Mail Answers
Answer Posted / a s n kumar (makson industri
.Both Matrixing & Bracketing’s are reduced stability testing designs
Bracketing
The design of a stability schedule, such that only samples of extremes of certain design factors (ex:strength,package size) are tested at all time points as in full design.The designs assumes that the stability of any intermediate level is represented by the stability of extremes tested.
Matrixing
The design of a stability schedule, such that a selected subset of possible samples for all factor combinations is tested at a specified time point.At a subsequent time point another subset of samples for all factor combination is tested.The design assumes that the stability of each subset samples tested represents the stability of all samples at a given time point.
There for a given time point other than initial & final ones not every batch on stability needs to be tested.
| Is This Answer Correct ? | 5 Yes | 2 No |
Post New Answer View All Answers
mahagenco syllabus for the post of chemist
How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.
what is the principle involved in turbidometry and nephelometry ?
process of Diclofenac sodium,IP.
what are the standard methods for HPLC?
If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?
which situation gc hs and gc als require to use?
Why potassium dichromate is used in calibration of uv?
In HPLC (Waters) software Empower1,2 &3 what is the updation for each version
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
how to calculate elemental impurities?
How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?
How you develop a method in HPLC?
Basic principle of ESI?
How to choose the which salt is suitable for mobilephase
