Answer Posted / psreddy

1.Select the raw material from the latest consignments and
identify which consignment is closest to 100% purity
2.Following tests compared with reference standard.
a.Description
b.Identification
c.Loss on drying/water content
d.Assay (Thrice)
3.Acceptance criteria :

i.The % RSD of the values obtained by both
chemists is NMT 2.0%.

ii.The % RSD of the values obtained by
individual chemist is NMT

how you start the solubility study?

805

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What is the Formula for coreletion coefficient in plhplc calibration

1806

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what is procedure of actual procedure for registration of drug?

1994

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What is the purpose of octyl silane columns?

4280

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acceptance criteria for lod & loq by standard deviation of response and slope??

2572

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2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

2202

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[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

759

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How can we confirm the HPLC column is end-capped or not? Is it possible to identify by physical appearance?

3196

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Difference between the quantitative analysis and qualitative analysis?

1147

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before starting analytical method valodation what you checking? and how giving preference to start validation?

780

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How to choose the which salt is suitable for mobilephase

3223

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what is turbidimetric titration?Give 2 examples.

2639

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Why Ethanol is Used for Standardization of GC Head space?

4214

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what is partion and column chromatography

2368

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Why sodium hydroxide used for maintain pH of phosphate buffer

2385

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