Answer Posted / developer

In general columns like C8 and C18 brands they mention
particle size like 3micron or 5 micron. But for chiral
columns also separation effect on the particle size we can
see good resolution with low particle size. For chiral
columns they mention for example chiradex for a particlular
particle size and for low partical size it could be
mentioned as chiradex-HS.

what is the origin to prepare standard operating procedure

2246

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What is similarity factor and its use in api strength?

1243

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

795

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How you develop a method in HPLC?

2557

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how you start RS method development when for new product?

657

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for inorganic molecules require to do RS, Assay and disso?

668

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For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?

2259

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How will u perform degradation study in detectors other thann PDA in HPLC Methodology

2474

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what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1921

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What is the use of tlc and hplc? And when and where use?

1094

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what is the disso medium for tropsiun chloride

2208

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What is shaking level in GC?

736

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How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium

2486

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can i use hplc detector to uplc and why?

2236

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In IR spectra, generally a molecule vibrates without apply emr or ir light?

1904

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